Spatiotemporal Dynamic Simulation of Acute Perfusion/Diffusion Ischemic Stroke Lesions Evolution: A Pilot Study Derived from Longitudinal MR Patient Data

Figure 4

Time-indexed penumbra and core lesion boundaries combined to final T2-weighted boundary imaged at >1 month. (b) MTT manually delineated penumbra boundaries consecutively at 𝑡₁ (in orange), 𝑡₂ (in yellow), and 𝑡₃ (in red). (a) DWI lesion boundaries ranging from light to dark blue as time evolves from 𝑡₁ to 𝑡₂ and then 𝑡₃. In both MR axial slices, the final T2 boundary is displayed in green shading.