Research Article

Modeling the Chemoelectromechanical Behavior of Skeletal Muscle Using the Parallel Open-Source Software Library OpenCMISS

Figure 1

Overview of the modeling framework. Each box indicates a model part. The couplings between the parts are indicated through arrows together with the transferred information. The membrane voltage, , couples the half-sarcomere model to the diffusion equation. Together, they represent the electrophysiological behavior of the muscle fiber. Further, is the shortening velocity, and is the active stress. The model of the motoneuron pool is not part of the proposed model, which is symbolized by a dashed box.
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