Comparison of Simple Models of Periodic Protocols for Combined Anticancer Therapy

Table 3

Results of anti-angiogenic therapy combined with chemotherapy for different periods and dosage.

Period	Total time of treatment	Tumor value after periodic treatment with dose of cytostatics inhibitors 1 mg kg^−1 day^−1
		Anti-angiogenic agents dose 2 mg kg^−1 day^−1	Anti-angiogenic agents dose 20 mg kg^−1 day^−1
2 days	50 days	3525.1 mm^3	1179.8 mm^3
3 days	48 days	3402.4 mm^3	1265.1 mm^3
4 days	48 days	3267.5 mm^3	1306.9 mm^3
5 days	50 days	3121.1 mm^3	1315.0 mm^3
6 days	48 days	3019.0 mm^3	1337.2 mm^3
7 days	49 days	2891.9 mm^3	1334.3 mm^3
8 days	48 days	2781.7 mm^3	1338.4 mm^3
9 days	45 days	2689.0 mm^3	1351.5 mm^3
10 days	50 days	2576.8 mm^3	1312.2 mm^3
11 days	44 days	2492.2 mm^3	1339.6 mm^3
12 days	48 days	2400.3 mm^3	1301.4 mm^3
13 days	39 days	2333.0 mm^3	1360.0 mm^3
14 days	42 days	2241.6 mm^3	1318.6 mm^3