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Computational and Mathematical Methods in Medicine
Volume 2013, Article ID 627976, 7 pages
Research Article

Automated Conduction Velocity Analysis in the Electrohysterogram for Prediction of Imminent Delivery: A Preliminary Study

1Maxima Medical Center, P.O. Box 7777, 5500 MB Veldhoven, The Netherlands
2Department of Electrical Engineering, University of Technology Eindhoven, Eindhoven, The Netherlands

Received 29 May 2013; Accepted 1 October 2013

Academic Editor: Mihaela Ungureanu

Copyright © 2013 Hinke de Lau et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background. Analysis of the electrohysterogram (EHG) is a promising diagnostic tool for preterm delivery. For the introduction in the clinical practice, analysis of the EHG should be reliable and automated to guarantee reproducibility. Study Goal. Investigating the feasibility of automated analysis of the EHG conduction velocity (CV) for detecting imminent delivery. Materials and Methods. Twenty-two patients presenting with uterine contractions (7 preterm) were included. An EHG was obtained noninvasively using a 64-channel high-density electrode grid. Contractions were selected based on the estimated intrauterine pressure derived from the EHG, the tocodynamometer, and maternal perception. Within the selected contractions, the CV vector was identified in two dimensions. Results. Nine patients delivered within 24 hours and were classified as a labor group. 64 contractions were analyzed; the average amplitude of the CV vector was significantly higher for the labor group, 8.65 cm/s ± 1.90, compared to the nonlabor group, 5.30 cm/s ± 1.47 . Conclusion. The amplitude of the CV is a promising parameter for predicting imminent (preterm) delivery. Automated estimation of this parameter from the EHG signal is feasible and should be regarded as an important prerequisite for future clinical studies and applications.