In Vivo Imaging-Based Mathematical Modeling Techniques That Enhance the Understanding of Oncogene Addiction in relation to Tumor Growth

Figure 6

Simulated tumor growth kinetics with a low (but nonzero) rate of tumor cells escaping from conditional control of MYC due to a compromised immune system. Note the early growth kinetics of the escaped tumor cell population demonstrates stochastic variability that affects the timing of the relapse.