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Computational and Mathematical Methods in Medicine
Volume 2013, Article ID 856897, 6 pages
http://dx.doi.org/10.1155/2013/856897
Research Article

Analysis of a Single Hemodialysis on Phosphate Removal of the Internal Fistula Patients by Mathematical and Statistical Methods

1Departments of Nephrology, The Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, China
2Departments of Radiation Oncology, The Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, China

Received 14 May 2013; Revised 7 September 2013; Accepted 30 September 2013

Academic Editor: Tianye Niu

Copyright © 2013 Qiyao Yu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Chronic kidney disease related mineral and bone disease (CKD-MBD) is a worldwide challenge in hemodialysis patients. In china, the number of dialysis patients is growing but few data are available about their bone disorders. In the current study, we aimed to evaluate the effect of clinical factors on the serum phosphorus clearance in the 80 maintenance hemodialysis (MHD) patients. Six clinical factors were identified for their association with the serum phosphorus clearance using the analysis of Spearman’s single linear correlation, including predialysis serum phosphate level, CRR, membrane surface area of the dialyzer, effective blood flow rate, the blood chamber volume, and hematocrit. In an overall multivariate analysis, pre-P, CRR, membrane SA, and Qb were identified as independent risk factors associated with the serum phosphorus clearance. In conclusion, HD could effectively clear serum phosphorus. The analysis of CRR might help to estimate serum phosphorus reduction ratio.