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Computational and Mathematical Methods in Medicine
Volume 2014 (2014), Article ID 867289, 15 pages
http://dx.doi.org/10.1155/2014/867289
Research Article

Systematic Analysis of Time-Series Gene Expression Data on Tumor Cell-Selective Apoptotic Responses to HDAC Inhibitors

1National Engineering Laboratory for Druggable Gene and Protein Screening, Northeast Normal University, Changchun 130024, China
2School of Computer Science and Information Technology, Northeast Normal University, Changchun 130117, China
3Department of General Internal Medicine, First Hospital of Jilin University, Changchun 130021, China
4Research Center of Agriculture and Medicine Gene Engineering of Ministry of Education, Northeast Normal University, Changchun 130024, China

Received 13 June 2014; Accepted 7 August 2014; Published 13 October 2014

Academic Editor: Hsueh-Fen Juan

Copyright © 2014 Yun-feng Qi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Table S1. H-score of all pathways for tumor and normal samples: This table lists the name, category, website and H-score values for all 1307 pathway.

Table S2. Illustrative pathways belonging to term "No responding": This table lists the name, category, website and TVPC patterns for "No responding" pathways.

Table S3. Illustrative pathways belonging to term "Consistent responding": This table lists the name, category, website and TVPC patterns for "Consistent responding" pathways.

Table S4. Illustrative pathways belonging to term "Tumor specific responding": This table lists the name, category, website and TVPC patterns for "Tumor specific responding" pathways.

Table S5. Illustrative pathways belonging to term "Normal specific responding": This table lists the name, category, web site and TVPC patterns for "Normal specific responding" pathways.

Table S6. Illustrative pathways belonging to term "Divergent responding": This table lists the name, category, website and TVPC patterns for "Divergent responding" pathways.

Table S7. Genes within profile #0 for normal samples: This table contains all genes within profile #0 for normal samples, and lists the normalized expression data to the right of gene symbol.

Table S8. Genes within profile #2 for normal samples: This table contains all genes within profile #2 for normal samples, and lists the normalized expression data to the right of gene symbol.

Table S9. Genes within profile #9 for normal samples: This table contains all genes within profile #9 for normal samples, and lists the normalized expression data to the right of gene symbol.

Table S10. Genes within profile #12 for normal samples: This table contains all genes within profile # 12 for normal samples, and lists the normalized expression data to the right of gene symbol.

Table S11. Genes within profile #14 for normal samples: This table contains all genes within profile #14 for normal samples, and lists the normalized expression data to the right of gene symbol.

Table S12. Genes within profile #0 for tumor samples: This table contains all genes within profile #0 for tumor samples, and lists the normalized expression data to the right of gene symbol.

Table S13. Genes within profile #2 for tumor samples: This table contains all genes within profile #2 for tumor samples, and lists the normalized expression data to the right of gene symbol.

Table S14. Genes within profile #5 for tumor samples: This table contains all genes within profile #5 for tumor samples, and lists the normalized expression data to the right of gene symbol.

Table S15. Genes within profile #12 for tumor samples: This table contains all genes within profile #12 for tumor samples, and lists the normalized expression data to the right of gene symbol.

Table S16. Genes within profile #14 for tumor samples: This table contains all genes within profile #14 for tumor samples, and lists the normalized expression data to the right of gene symbol.

Table S17. GO terms enriched for "Invariant" profile pairs: This table lists the ID, name, P-value and corrected P-value for GO terms enriched for "Invariant" profile pairs.

Table S18. GO terms enriched for "Minitrim" profile pairs: This table lists the ID, name, P-value and corrected P-value for GO terms enriched for "Minitrim" profile pairs.

Table S19. GO terms enriched for "Reversion" profile pairs: This table lists the ID, name, P-value and corrected P-value for GO terms enriched for "Reversion" profile pairs.

  1. Supplementary Tables