Dynamic Regulatory Network Reconstruction for Alzheimer’s Disease Based on Matrix Decomposition Techniques

<table>Dynamic transcriptional regulatory network for AD. Transcriptional regulatory network of (a) control, (b) incipient, (c) moderate, and (d) severe AD samples. Diamond in the middle denoted TFs with activity values in different colors, circles with different colors presented the gene expression of target genes, and the lines between TFs and target genes with different colors noted the control strength.</table>

Computational and Mathematical Methods in Medicine

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Figure 2: Dynamic Regulatory Network Reconstruction for Alzheimer’s Disease Based on Matrix Decomposition Techniques 