First Comprehensive In Silico Analysis of the Functional and Structural Consequences of SNPs in Human GalNAc-T1 Gene

Table 5

Total energy of native and mutant structures before and after energy minimization.

Amino acid variants	Total energy before energy minimization (kJ/mol)	Total energy after energy minimization (kJ/mol)
Native	13140.137	−13882.539
S143P	13392.757	−13767.374
G258V	59777.910	−10727.144
Y414D	12995.687	−13918.198