Comparison of Two Methods Forecasting Binding Rate of Plasma Protein

Table 1

Correlation matrix of the six descriptors^a.

Descriptor	1	2	3	4	5	6
1	1.000	0.177	0.776	0.039	−0.190	−0.559
2		1.000	0.266	0.269	−0.104	−0.255
3			1.000	0.129	−0.541	−0.592
4				1.000	−0.192	−0.497
5					1.000	0.325
6						1.000

a1: ALFA polarizability (DIP), 2: WPSA-3 weighted PPSA (Zefirov’s PC), 3: HASA-1/TMSA (Zefirov’s PC), 4: Tot point-charge compd. of the molecular dipole, 5: PNSA-2 total charge weighted PNSA, and 6: final heat of formation.