Multimodality Functional Imaging in Radiation Therapy Planning: Relationships between Dynamic Contrast-Enhanced MRI, Diffusion-Weighted MRI, and 18F-FDG PET

Table 2

Main parameters of the Tofts model.

Quantity	Definition
	Arterial concentration as a function of time
	Tissue concentration as a function of time
	Hematocrit volume
	Transfer constant from the blood plasma into the EES
	Transfer constant from the EES back to the blood plasma
	Onset time of arterial contrast uptake
	Whole blood volume per unit of tissue
	Total EES volume ()