Research Article

Nonsynonymous Single-Nucleotide Variations on Some Posttranslational Modifications of Human Proteins and the Association with Diseases

Table 3

Numbers and values of ±2 AA matched nsSNVs related to inherited diseases and cancer on each PTM.

PTMGenetic disease valueCancer value

Phosphorylation1422128260.0111
Ubiquitylation4394074
Acetylation5524019
Glycosylation2140.0261795
Methylation440.1036231
SUMOylation110.1526115
Hydroxylation220.199763
Sulfation70.244690.2526

values in this column were calculated using hypergeometric test and all values refer to the left column (genetic disease).