Monte Carlo Calculation of Radioimmunotherapy with ⁹⁰Y-, ¹⁷⁷Lu-, ¹³¹I-, ¹²⁴I-, and ¹⁸⁸Re-Nanoobjects: Choice of the Best Radionuclide for Solid Tumour Treatment by Using TCP and NTCP Concepts

Figure 5

TCP values for a 1.0 cm radius tumour, calculated in %, as a function of the number of radioactive atoms included in each NO when the covering fraction corresponds to 10¹⁰ mAbs/cm² and days. TCP curves are represented for ⁹⁰Y-NOs, ¹⁷⁷Lu-NOs, ¹⁸⁸Re-NOs, ¹³¹I-NOs, and ¹²⁴I-NOs distributed uniformly, linearly, and exponentially throughout the tumour. For each graph, TCP curves are compared to NTCP curves to predict lung complications risks.