Computational and Mathematical Methods in Medicine / 2015 / Article / Tab 1

Research Article

Identifying New Candidate Genes and Chemicals Related to Prostate Cancer Using a Hybrid Network and Shortest Path Approach

Table 1

The top six KEGG pathways shared by 187 significant candidate genes.

Pathway IDPathway nameGenes sharing the pathwayFDR

hsa05200Pathways in cancerFGF6, FGFR2, TRAF2, FGFR1, PDGFB, WNT3A, MITF, NFKB1, TGFB1, CTNNB1, GLI1, MAX, WNT1, CASP3, RARA, HHIP, AXIN1, PIK3R2, CREBBP, CDK6, BIRC2, RALGDS, CCND1, PLCG1, NTRK1, MAPK3, PDGFRB, PTCH1, IKBKB, and GSTP1

hsa04010MAPK signaling pathwayFGFR2, FGF6, TRAF2, FGFR1, PDGFB, PPP3R1, NFKB1, TGFB1, ATF2, MAP3K7, MAX, TNFRSF1A, CASP3, MAP3K5, MAP3K3, MAP2K6, RASA1, FLNA, MAPK14, NTRK1, GADD45G, MAPK3, PDGFRB, HSPB1, IKBKB, CD14, and DUSP6

hsa05215Prostate cancerFGFR2, FGFR1, CCND1, PDGFB, MAPK3, CREBBP, PDGFRB, NFKB1, IKBKB, GSTP1, CTNNB1, and PIK3R2

hsa05214GliomaCCND1, PLCG1, PDGFB, CAMK2G, MAPK3, PDGFRB, CDK6, SHC1, CALM2, and PIK3R2

hsa04722Neurotrophin signaling pathwayCAMK2G, NFKB1, MAGED1, MAP3K5, MAP3K3, PLCG1, NTRK1, MAPK14, MAPK3, SHC1, IKBKB, CALM2, and PIK3R2

hsa04310Wnt signaling pathwayROCK1, WNT3A, CAMK2G, CREBBP, CSNK2B, PPP3R1, CTNNB1, MAP3K7, WNT1, CCND1, CSNK1E, LRP6, LRP5, and AXIN1

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