Unified Modeling of Familial Mediterranean Fever and Cryopyrin Associated Periodic Syndromes

Table 1

CAPS types and their symptoms.

Disease	Major symptoms	Severity
FCAS	Cold-induced urticarial rash and arthralgia; Fever after exposure to cold	The mildest
MWS	Shared symptoms with FCAS and NOMID; Inflammation is seen without provocation; Cold, stress, and exercise also trigger the inflammation	Intermediate
NOMID	Neonatal-onset high fever, persistent rash, aseptic meningitis, mental retardation, sensory deafness, papilledema, arthritis with bone overgrowth, and secondary amyloidosis	The most severe