Review Article

Comparative Transcriptomes and EVO-DEVO Studies Depending on Next Generation Sequencing

Figure 2

Illustration of the two major models about the selective pressure of embryonic development and their measurement. Pictorial charts in the right side stand for the “funnel-like” model and “hourglass” model. Histograms, boxplots, and lines from left to right stand for the three kinds of measurement of selective pressure based on transcriptomic data. In the figure of expression correlation, higher expression correlation means transcriptome similarity, which is the signature of conservation. In the figure of dN/dS ratio, lower dN/dS ratio means the conserved gene sequences. For the computation of transcriptome age index, ancient genes are labeled with small numbers while young genes are labeled with big numbers. Therefore, lower transcriptome age index of a stage means more ancient genes expressing in corresponding stages in the figure of transcriptome age index.
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