Modeling the Interaction between <i>β</i>-Amyloid Aggregates and Choline Acetyltransferase Activity and Its Relation with Cholinergic Dysfunction through Two-Enzyme/Two-Compartment Model

<div>Possible noncompetitive inhibition mechanisms for <i>β</i>-amyloid aggregates during pH-dependent ChAT synthesis of ACh: E = ChAT, I = <i>β</i>-amyloid aggregates, A = choline, B = acetyl-coA, and Products = ACh.</div>

Computational and Mathematical Methods in Medicine

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Figure 16

Figure 16: Modeling the Interaction between <i>β</i>-Amyloid Aggregates and Choline Acetyltransferase Activity and Its Relation with Cholinergic Dysfunction through Two-Enzyme/Two-Compartment Model 

Figure 16 | Modeling the Interaction between β-Amyloid Aggregates and Choline Acetyltransferase Activity and Its Relation with Cholinergic Dysfunction through Two-Enzyme/Two-Compartment Model 