Research Article

Modeling the Interaction between β-Amyloid Aggregates and Choline Acetyltransferase Activity and Its Relation with Cholinergic Dysfunction through Two-Enzyme/Two-Compartment Model

Table 2

Values of the kinetic parameters.

ParameterValueReference

5.2 (0.1)[5, 6, 29]
12[5, 6]
1000[5, 6]
5[5, 6]
1[5, 6]
0.5[3034]
1[3034]
1.066  10−6 kMole/m3 (Mole/mm3)[3034]
50.33 Mole/L[3034]
100 Mole/L[35]
1 Mole/L[35]
 kMole/m3 (Mole/mm3)[30]
 kMole/m3 (Mole/mm3)[30]
2.25[33]
0.5[33]
1.5[33]
1.5[33]
1[33]
1.2[33]
8.2 [35]
15[30]
1.15[30]
3.9[30]
0.01[3034]
0.8[36, 37]
20 nM/h[22, 28]
Assumed
Assumed
Assumed
Assumed
10.015Assumed
0.05Assumed
0.1 hAssumed
20 nM/L[23]