Research Article
A Canonical Correlation Analysis of AIDS Restriction Genes and Metabolic Pathways Identifies Purine Metabolism as a Key Cooperator
Table 3
Cross-correlation of Hf genes with canonical variate.
| Gene symbol | | | | | | | | |
| DEFB1 | 0.01 | 0.01 | 0.02 | −0.15 | 0.06 | −0.02 | −0.14 | −0.04 | KIR | 0.08 | −0.02 | −0.05 | −0.01 | −0.14 | 0.08 | 0.17 | −0.12 | GML | −0.17 | −0.16 | 0.12 | −0.06 | 0.21 | −0.06 | 0.03 | 0.07 | HLA-A | 0.10 | −0.14 | −0.01 | 0.00 | −0.03 | −0.22 | −0.13 | −0.09 | HLA-B | 0.10 | 0.09 | 0.12 | 0.12 | −0.41 | 0.25 | 0.07 | −0.31 | HLA-C | 0.07 | −0.26 | −0.04 | −0.08 | 0.21 | −0.33 | −0.22 | −0.21 | IDH1 | 0.28 | 0.17 | −0.22 | −0.17 | 0.60 | −0.20 | 1.12 | 0.63 | IFENG | 0.00 | 0.03 | 0.08 | 0.07 | 0.05 | −0.09 | −0.12 | −0.07 | IL4 | −0.12 | −0.18 | 0.08 | 0.05 | 0.01 | −0.10 | −0.15 | 0.30 | CXCR1 | −0.07 | −0.25 | 0.20 | 0.00 | 0.17 | −0.40 | −0.14 | 0.08 | IL10 | −0.02 | −0.05 | 0.02 | 0.13 | 0.05 | −0.04 | −0.05 | −0.01 | IRF1 | 0.07 | −0.09 | 0.08 | 0.10 | 0.23 | −0.24 | −0.14 | −0.24 | MYH9 | 0.36 | −0.17 | 0.21 | −0.14 | −0.49 | −0.50 | 0.14 | −0.19 | PPIA/CypA | 0.42 | 0.92 | 1.88 | 0.58 | −0.54 | 1.11 | 0.00 | 1.12 | PROX1 | −0.14 | 0.07 | 0.03 | 0.16 | 0.23 | 0.02 | 0.55 | −0.66 | Slurp2/Ly6 | −0.04 | −0.03 | 0.00 | 0.10 | −0.13 | 0.12 | 0.09 | 0.02 | CCL2 | 0.02 | −0.03 | −0.04 | 0.00 | −0.05 | 0.12 | 0.08 | 0.00 | CCL4 | 0.02 | −0.06 | 0.02 | 0.09 | 0.02 | 0.05 | 0.04 | −0.06 | CCL5 | 0.03 | −0.06 | 0.01 | 0.03 | 0.00 | 0.02 | −0.14 | 0.05 | CCL11 | 0.02 | −0.05 | 0.01 | 0.02 | 0.09 | −0.01 | 0.25 | −0.05 | CCL17 | 0.00 | −0.06 | 0.05 | 0.07 | 0.06 | −0.02 | −0.19 | −0.06 | CCL18 | 0.03 | −0.04 | 0.00 | 0.06 | 0.05 | 0.14 | 0.09 | 0.05 | SDF1/CXCL12 | 0.09 | −0.10 | −0.17 | −0.18 | −0.26 | 0.14 | 0.09 | 0.22 | TLR4 | 0.06 | −0.05 | −0.02 | 0.24 | −0.15 | 0.26 | 0.00 | 0.02 | TSG101 | 0.31 | 0.48 | −0.25 | −0.05 | 0.17 | 0.49 | −0.54 | −1.03 | CUL5 | 0.15 | 0.51 | −0.87 | −0.23 | 0.19 | 0.40 | −0.80 | −0.04 | LY6D | 0.01 | −0.05 | 0.10 | −0.24 | 0.10 | 0.13 | 0.01 | −0.08 | APOBEC3B | 0.04 | 0.03 | 0.04 | 0.03 | 0.15 | −0.12 | 0.02 | 0.14 | NCOR2 | −0.31 | −0.28 | 0.37 | −0.27 | −1.10 | −0.24 | −0.38 | 0.52 | PECI/ECI2 | 0.09 | 0.15 | −0.24 | 0.01 | −0.10 | 0.06 | −0.35 | 0.25 | CXCR6 | −0.06 | −0.10 | 0.02 | −0.06 | 0.03 | 0.18 | −0.07 | 0.09 | HCP5 | −0.04 | 0.02 | −0.01 | −0.01 | 0.32 | 0.01 | 0.02 | −0.01 | ZNRD1 | 0.37 | 0.14 | 0.28 | −0.03 | 0.32 | −0.91 | −0.04 | 0.10 | DC-SIGN | −0.04 | −0.29 | 0.13 | 0.00 | −0.17 | 0.03 | 0.22 | 0.33 | TLR8 | 0.13 | −0.36 | −0.03 | 0.30 | 0.33 | 0.70 | −0.15 | 0.17 | TLR9 | −0.03 | −0.18 | 0.11 | −0.06 | −0.02 | −0.17 | −0.24 | 0.36 | Slurp1 | −0.03 | −0.10 | 0.19 | −0.61 | 0.21 | 0.32 | 0.04 | −0.06 | APOBEC3G | 0.06 | −0.17 | −0.14 | 0.11 | 0.19 | 0.07 | −0.44 | 0.39 | TRIM5a | 0.17 | −0.13 | −0.15 | 0.00 | 0.26 | −0.30 | 0.22 | 0.53 |
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