Research Article

Role of CaMKII and PKA in Early Afterdepolarization of Human Ventricular Myocardium Cell: A Computational Model Study

Table 2

Combined effect of CaMKII overexpression and β-adrenergic agonist on EADs.

Cycle length (ms)ISO applicationCaMKII target (CaMK0 = 0.12) blockage level (%)EADs

2000NoneNone85None
1 µMNone85Yes
None77No
85Yes
77Yes
85Yes
77No