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Computational and Mathematical Methods in Medicine
Volume 2016, Article ID 4846738, 14 pages
http://dx.doi.org/10.1155/2016/4846738
Research Article

Microwave Ablation Using Four-Tine Antenna: Effects of Blood Flow Velocity, Vessel Location, and Total Displacement on Porous Hepatic Cancer Tissue

Department of Electronic Engineering, Faculty of Engineering, King Mongkut’s Institute of Technology Ladkrabang, Bangkok 10520, Thailand

Received 11 March 2016; Revised 12 May 2016; Accepted 30 June 2016

Academic Editor: Enrique Berjano

Copyright © 2016 Montree Chaichanyut and Supan Tungjitkusolmun. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

This research is concerned with microwave ablation analyses using a 2.45 GHz four-tine (4T) antenna for hepatic cancer tissue. In the study, three-dimensional finite-element models were utilized to examine the tissue temperature distributions during and after MW ablation. A preliminary study was first carried out with regard to the specific absorption rates along the 4T antenna insertion depths and the temperature distributions inside the solid and porous liver models with either 3 cm-in-diameter tumor or 5 cm-in-diameter tumor. Based on the preliminary results, the porous models were further examined for the effect of varying blood flow velocities (0–200 cm/s) with a 1 cm-in-diameter blood vessel next to the antenna and also for the effect of vessel-antenna locations (0, 0.8, and 1.3 cm) with a constant blood flow velocity of 16.7 cm/s. All scenarios were simulated under temperature-controlled mode (90°C). The findings revealed that the blood flow velocity and vessel location influence the ablation effectiveness and that increased blood flow inhibits heat transfer to the vessel wall. At the nearest and farthest vessel-antenna locations (0 and 1.3 cm), approximately 90.3% and 99.55% of the cancer cells were eradicated except for the areas adjacent to the vessel. In addition, total tissue thermal displacement is 5.9 mm which is 6.59% of the total length of the overall model.