Towards the Design of a Patient-Specific Virtual Tumour

Figure 3

Stages of the procedure to transpose the bright field image information of the vascular network into the computational framework. (a) Bright field image of the vasculature; (b) the main vessels segmented; (c) the image cropped to the region of interest; (d) the vascular network perfused at the entry point highlighted by the black dot and vascular adaptation simulated until a stationary state is reached; (e) the resulting adapted vasculature merged with the extracted information on the tumour cells distribution. The procedure is illustrated here on tumour case M4-L.