In Silico Evaluation of the Potential Antiarrhythmic Effect of Epigallocatechin-3-Gallate on Cardiac Channelopathies

Table 4

The effect of E3G on conduction velocity investigations in the presence of p.R222Q and p.I141V in heterozygous states.

Model	Atrial cells		Ventricular cells		Purkinje cells
Condition	CV (cm/s); control	CV (cm/s); 30 µM E3G	CV (cm/s); control	CV (cm/s); 30 µM E3G	CV (cm/s); control	CV (cm/s); 30 µM E3G
WT	55.07	50.84	49.91	45.72	67.68	37.20
p.I141V	57.44	53.93	53.63	49.11	72.43	42. 92
p.R222Q	60.93	56.23	51.93	45.56	62.72	—