Research Article

Peritoneal Fluid Transport rather than Peritoneal Solute Transport Associates with Dialysis Vintage and Age of Peritoneal Dialysis Patients

Table 1

Peritoneal transport characteristics (mean ± SD) from miniPET (after 1 h dwell) and PET (after 4 h dwell) and their correlations (expressed as Spearman correlation coefficient rho) with creatinine D/P, patient age, and dialysis vintage, for 33 prevalent peritoneal dialysis patients.

ParametersParameter valueCorrelation with
creatinine D/P
Correlation with ageCorrelation with
dialysis vintage

miniPET
Net ultrafiltration [mL]375 ± 107NS−0.62NS
Ultrafiltration through small pores [mL]168 ± 107NS−0.36−0.37
Free water transport [mL]207 ± 62NS−0.41NS
Free water fraction [%]58 ± 20NSNS0.37
D/P sodium0.85 ± 0.030.570.38NS
Dip D/P sodium0.077 ± 0.028NSNSNS
Albumin clearance0.127 ± 0.0490.68NSNS
PET
Net ultrafiltration [mL]168 ± 168−0.47−0.53NS
D/P creatinine0.66 ± 0.101.00NSNS
D/D0 glucose0.36 ± 0.07−0.85NSNS
Albumin clearance0.099 ± 0.0380.78NSNS
IgM clearance0.020 ± 0.0130.58NSNS

Net ultrafiltration (netUF60) was defined as the difference between the weight of the effluent (Vend) and the weight of the infused peritoneal dialysis fluid (V0); ultrafiltration through small pores UFSP60 = RemNa/CBNa, where sodium removal RemNa = Vend CNaEnd − V0 CNa0; free water transport FWT = netUF60 − UFSP60; free water fraction FWF = FWT/netUF60.
D/P sodium, dialysate to plasma sodium concentration (D/PNa) at the end (D/PNa60) of miniPET; dip D/P sodium, sodium dip DipNa60 = D/PNa0 − D/PNa60; NS, not significant.