A Multiscale Model for the World’s First Parasitic Disease Targeted for Eradication: Guinea Worm Disease

Table 5

Within-host parameter values of the model system (1).

Parameter	Description	Initial values	Units	Source
	Fecundity rate of mature worms	700	People	Estimated
	Decay rate of copepods within a human host due to gastric juice	0.99	Copepod	Estimated
	Natural death rate of copepods within a human host	0.001		Estimated
	Natural decay rate of mature worms within a human host	0.9		Estimated
	Migration rate of mature worms to subcutaneous tissues	0.9		Estimated
	Natural death rate of fertilized female worms within a human host	0.9		Estimated
	Migration rate of fertilized female worms to surface of skin	0.07		Estimated
	Dilution/degradation rate of gastric juice	0.05		Estimated
	Proliferation rate of gastric juice due to infection	0.4		Estimated
	Supply rate of gastric juice from within a human body	1.5		Estimated