Research Article
A Multiscale Model for the World’s First Parasitic Disease Targeted for Eradication: Guinea Worm Disease
Table 5
Within-host parameter values of the model system (
1).
| Parameter | Description | Initial values | Units | Source |
| | Fecundity rate of mature worms | 700 | People | Estimated | | Decay rate of copepods within a human host due to gastric juice | 0.99 | Copepod | Estimated | | Natural death rate of copepods within a human host | 0.001 | | Estimated | | Natural decay rate of mature worms within a human host | 0.9 | | Estimated | | Migration rate of mature worms to subcutaneous tissues | 0.9 | | Estimated | | Natural death rate of fertilized female worms within a human host | 0.9 | | Estimated | | Migration rate of fertilized female worms to surface of skin | 0.07 | | Estimated | | Dilution/degradation rate of gastric juice | 0.05 | | Estimated | | Proliferation rate of gastric juice due to infection | 0.4 | | Estimated | | Supply rate of gastric juice from within a human body | 1.5 | | Estimated |
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