Utilizing Selected Di- and Trinucleotides of siRNA to Predict RNAi Activity

Table 2

Primary trinucleotides with minimal value.

Position	Trinucleotide motif	Freq; ()	Freq; ()	Type of corr.	value
1	UUG1	52/1218	5/1213	Positive
	GGG1	4/1218	50/1213	Negative
2	UUA2	14/1218	4/1213	Positive
	GCC2	10/1218	33/1213	Negative
3	AUU3	28/1218	9/1213	Positive
	CAC3	9/1218	29/1213	Negative
4	UAU4	19/1218	5/1213	Positive
	CCA4	19/1218	41/1213	Negative
5	AUU5	29/1218	11 /1213	Positive
	CCC5	6/1218	30/1213	Negative
6	UUU6	40/1218	12/1213	Positive
	CCA6	10/1218	41/1213	Negative
7	UCU7	37/1218	18/1213	Positive
	CGU7	3/1218	16/1213	Negative
8	ACA8	29/1218	13/1213	Positive
	AAU8	8/1218	28/1213	Negative
9	CAA9	26/1218	7/1213	Positive
	AUU9	12/1218	30/1213	Negative
10	ACA10	35/1218	11/1213	Positive
	CGA10	2/1218	12/1213	Negative
11	CUA11	32/1218	13/1213	Positive
	GCG11	6/1218	23/1213	Negative
12	AUU12	30/1218	11/1213	Positive
	GGG12	9/1218	31/1213	Negative
13	UUU13	33/1218	16/1213	Positive
	CCG13	6/1218	20/1213	Negative
14	CCA14	36/1218	16/1213	Positive
	CCC14	6/1218	21/1213	Negative
15	UAU15	16/1218	4/1213	Positive
	UGG15	19/1218	46/1218	Negative
16	ACU16	31/1218	12/1213	Positive
	CGA16	1/1218	10/1213	Negative
17	CUG17	49/1218	21/1213	Positive
	GUU17	9/1218	34/1213	Negative
18	UCU18	43/1218	11/1213	Positive
	AAA18	8/1218	28/1213	Negative
19	CUG19	61/1218	16/1213	Positive
	AGA19	7/1218	31/1213	Negative