Preventing Neurodegenerative Memory Loss in Hopfield Neuronal Networks Using Cerebral Organoids or External Microelectronics

Figure 2

The memory sets encoded in the Hopfield networks are composed of 20 black and white pictures ( pixels) drawn from a larger collection of Unicode symbols. The upper set (in solid green) contains an optimal set of characters that are collectively less correlated (orthogonal) to each other. The lower set (in dashed pink) shares 15 memories with the optimal set but displays a noticeably worse performance. Each memory is paired with its corresponding, calibrated auxiliary memory pattern, encoded by the external network. Auxiliary memories are significantly smaller than the original ones ( pixels) and do not resemble the original patterns or form interpretable shapes.