A Review on the Extraction of Quantitative Retinal Microvascular Image Feature

Table 1

Association between retinal vessel diameter and stroke [19].

Outcome	Study	Total Sample size	Methodology	Association with Retinal Vessel Diameter
Prevalent stroke	CHS [6]	2050	Clinical	0
	CHS [40]	1717	MRI	AVR
	ARIC [28]	1684	MRI
Prevalent WML	ARIC [47]	1684	MRI	0
	CHS [40]	1717	MRI	AVR
	Rotterdam [48]	490	MRI	Venular diameter
Progression WML
3.3-year	Rotterdam [48]	490	MRI	Venular diameter
5-year	CHS [40]	1717	MRI	AVR
Incident stroke
3.3-year	Rotterdam [48]	490	MRI	0ƚ
3.5-year	ARIC [5]	10 358	Clinical	0
5-year	CHS [40]	1717	MRI	AVR
5-year	CHS [49]	1992	Clinical	Venular diameter
7-year	BMES [8]	3654	CT or MRI	0#
8.5-year	Rotterdam [50]	5540	CT or MRI	Venular diameter
10–12 years	Pooled BDES BMES [51]	7494	Clinical	0
Stroke mortality			ANDI
7-year	BMES [8]	3654	Death certificate	0
10-year	BDES [24]	413 cases		AVR
		1251 controls	Death
			certificate
10–12	Pooled BDES BMES [51]	7494	or ANDI	0