Computational Prediction of the Combined Effect of CRT and LVAD on Cardiac Electromechanical Delay in LBBB and RBBB

Figure 2

(a) The heterogeneous mesh that has the characteristics of endocardial, midmyocardial, and epicardial cells. (b) The CRT pacing site for the LBBB heart was placed on the LV free-wall, while that for the RBBB heart was placed inside the RV at the bottom of the septum. (c) The electrical propagation by the Purkinje network in the sinus, LBBB, and RBBB conditions. The electrical activation by the Purkinje networks is indicated in red. In sinus pacing, the Purkinje network delivers the electrical signal to its terminals. In the LBBB condition, the Purkinje network delivered the signal only to the right network in the RV area. In the RBBB condition, the Purkinje network delivered the signal only to the left network in the LV area. CRT, cardiac resynchronization therapy; LBBB, left bundle branch block; LV, left ventricular; RBBB, right bundle branch block; RV, right ventricular.

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