Research Article

Developing a Minimally Structured Mathematical Model of Cancer Treatment with Oncolytic Viruses and Dendritic Cell Injections

Table 1

Best-fit parameters for the system in Equations (1)–(6) to the Ad/4-1BBL/IL-12 and DC data, along with the corresponding 95% credible interval, as computed in [19]. Also shown is the maximum extent to which each parameter value can deviate from its best-fit value and still give a fit within 10% of the optimal, as determined through a local sensitivity analysis [19].

ParameterBest-fitMaximum % deviation from best-fit value95% credible interval

3%
0.7%
17,300%
47.2%
46.3%
7%