Developing a Minimally Structured Mathematical Model of Cancer Treatment with Oncolytic Viruses and Dendritic Cell Injections

Table 2

Best-fit parameter values for the minimal model in Equations (11)–(15), along with the change in the goodness-of-fit metric for the submodel of Ad/4-1BBL/IL-12 (Model 3c), and the full model for Ad/4-1BBL/IL-12 with DCs (Model 5). Also provided is the model number (which stage of the hierarchy) that was fit to arrive at the given parameter value. Once a value has been fit, it is used in all subsequent models.

Value	Best-fit (minimal model)	% deviation from original model	Model
		0%	1
		0%	2
		−15.92%	3c
		+4.7%	3
		+4.84%	4 and 5
Value	% change in from original model
	+3.05%
	−0.08%