Improved Specificity and False Discovery Rates for Multiplex Analysis of Changes in Strain-Specific Anti-Influenza IgG
Table 3
Examples of inconsistent results from pairwise comparisons with and without consideration of strain subtype variations in the clinical vaccine data analysis.
Group
Time in days
Group
Time in days
With consideration of subtype variation
Without consideration of subtype variation
SE of
value
SE of
value
MPR
0
MPR
3
0.3092
0.0643
0.1376
0.0825
0.0953
MPR
180
PR
180
0.1609
0.0956
0.0927
0.2062
0.0938
0.0281
PR
14
PR
180
−0.1812
0.0494
0.0002
−0.1139
0.0610
0.0620
PR
28
PR
180
−0.1056
0.0453
0.0198
−0.0762
0.0583
0.1913
UP
56
UP
208
0.3424
0.0842
0.0751
0.1031
0.4663
UP
180
UP
208
0.2689
0.0666
0.0843
0.0854
0.3237
SE = standard error; PR = primed group; MPR = multiply primed group; UP = unprimed group.
