Iterative Variable Gene Discovery from Whole Genome Sequencing with a Bootstrapped Multiresolution Algorithm

<div>V-genes in <i>Macaca mulatta</i>. Comparison of V-genes obtained from VgeneFinder and VgenExtractor for TRAV and TRBV against the Ensembl annotations. The gene annotations in <i>M. mulatta</i> are limited as described in the text. This comparison shows that our software tools correctly identify all the known annotated genes as well as identify the rest of the V-gene repertoire. The comparison between VgeneFinder and VgenExtractor shows that VgeneFinder is able to uncover sequences which are not canonical (as seen in the alignments).</div>

Computational and Mathematical Methods in Medicine

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Figure 8

Figure 8: Iterative Variable Gene Discovery from Whole Genome Sequencing with a Bootstrapped Multiresolution Algorithm 