Noninvasive Evaluation of Liver Fibrosis Reverse Using Artificial Neural Network Model for Chronic Hepatitis B Patients

Table 1

Patient characteristics at baseline and 78 w.

	Baseline (n = 298)	78 w (n = 141)	t/Z value
Gender, n (%)
Male	205 (68.8)	118 (73.8)	1.231	0.267
Female	93 (31.2)	42 (26.3)
Age
Mean ± SD	37.9 ± 10.8	36.2 ± 9.9	1.653	0.099
HBVDNA log10 (IU/ml)
Mean ± SD	6.1 ± 1.9	1.4 ± 0.3	31.067	<0.001
ALT (U/L)
Median (P25, P75)	82.7 (45.3, 160.8)	25.0 (17.0, 32.4)	15.555	<0.001
AST (U/L)
Median (P25, P75)	52.0 (35.9, 93.0)	24.3 (19.0, 30.0)	15.387	<0.001
PLT (E9/L)
Median (P25, P75)	168.0 (135.0, 202.0)	156.0 (117.0, 193.7)	2.700	0.007
WBC (E9/L)
Mean ± SD	5.4 ± 1.5	4.7 ± 1.6	4.651	<0.001
ALB (g/L)
Mean ± SD	43.0 ± 4.4	45.0 ± 4.2	4.711	<0.001
CHE (μmol/L)
Median (P25, P75)	3685.0 (7.2, 7243.0)	10.8 (8.2, 8412.3)	4.952	<0.001
TBIL (μmol/L)
Mean ± SD	17.4 ± 14.3	13.1 ± 5.9	3.639	<0.001
BUN (mmol/L)
Mean ± SD	4.6 ± 1.2	4.7 ± 1.3	0.826	0.409
Cr (μmol/L)
Mean ± SD	68.4 ± 14.5	66.1 ± 17.8	1.492	0.136
PT (s)
Mean ± SD	12.6 ± 1.4	11.7 ± 1.1	7.046	<0.001
LSM (kPa)
Median (P25, P75)	8.7 (6.7, 13.7)	6.2 (5.2, 8.2)	7.976	<0.001