Multiple-Strain Malaria Infection and Its Impacts on Plasmodium falciparum Resistance to Antimalarial Therapy: A Mathematical Modelling Perspective

Figure 10

Dynamics of drug-sensitive (blue) and drug-resistant (orange) strains in a single infection (a) and in a multiple infection (b) in a naive human-host with no malaria therapy (). The density of the resistant strain is lower than that of drug-sensitive strain for and in a multiple-strain P. falciparum infection. The rest of the parameter values are as displayed in Table 3.

(a)

(b)