Multiple-Strain Malaria Infection and Its Impacts on Plasmodium falciparum Resistance to Antimalarial Therapy: A Mathematical Modelling Perspective

Figure 7

The effect of varying the efficacy of antimalarial drug used and the rate of development of resistance by the drug-sensitive merozoites , on the density of infected erythrocytes . The value of ranges from 0 to 1. The rest of the parameter values are available in Table 3. Figure (c) shows that in the absence of highly effective ACTs, drug-resistant parasite would take a longer time to eradicate.

(a)

(b)

(c)