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| Parameter | Description |
|
| The rate of recruitment of red blood cells |
| Antimalarial treatment efficacy |
| Parasite strain-specific fitness cost |
| Background recruitment rate of immune cells |
| Hill parameters in , , and dynamics |
| Per capita natural mortality rate of unparasitized erythrocytes |
| Natural mortality rate of drug-sensitive IRBCs |
| Natural death rate of drug-resistant IRBCs |
| Rate of antimalarial eradication of merozoites and gametocytes, respectively |
| Death rate of drug-sensitive merozoites |
| Mortality rate of drug-resistant merozoites |
| Per capita mortality rate of drug-sensitive gametocytes |
| Mortality rate of drug-resistant gametocytes |
| Natural mortality rate of immune cells (CD8 + T cells) |
| β | The rate of infection of susceptible RBCs by blood floating merozoites |
| , | Rate of formation of gametocytes from the infected RBCs |
| P | Number of merozoites produced per dying infected RBC |
| Immune cell proliferation rate due to IRBCs |
| Immune cell proliferation rate due to asexual merozoites |
| Immune cell proliferation rate due to gametocytes |
| Phagocytosis rate of IRBCs by immune cell |
| Phagocytosis rate of merozoites by immune cell |
| Phagocytosis rate of gametocytes by immune cell |
| Rate of development of resistance by drug-sensitive merozoites |
| Rate of development of resistance by drug-sensitive gametocytes |
| Accounts for the reduced fitness of the resistant parasite strains |
| γ | Efficiency of immune effector to inhibit merozoite infection |
| Half-saturation constant for , , and |
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