HMMPred: Accurate Prediction of DNA-Binding Proteins Based on HMM Profiles and XGBoost Feature Selection

Table 1

Prediction results of SVM and RF classifiers based on the 10-fold CV.

Classifier	Feature extraction method	ACC	SN	SP	MCC	AUC
SVM	AAC	0.7893	0.8224	0.7582	0.5810	0.8586
	ACT	0.7004	0.6795	0.7200	0.3999	0.7492
	CCT	0.7678	0.7336	0.8000	0.5352	0.8309
	AAC+ACT+CCT	0.8034	0.8147	0.7927	0.6071	0.8717
RF	AAC	0.7772	0.8147	0.7418	0.5571	0.8600
	ACT	0.7369	0.7394	0.7345	0.4737	0.8022
	CCT	0.7566	0.7896	0.7255	0.5154	0.8232
	AAC+ACT+CCT	0.7781	0.8205	0.7382	0.5596	0.8437