Mathematical Modelling of HIV-HCV Coinfection Dynamics in Absence of Therapy

Table 1

HIV-HCV coinfection model parameters and their interpretations, where the appropriate units are year^-1.

Parameter	Symbol	Value	Source
HIV transmission probability per sexual contact		0.03604	[34]
HCV transmission probability per sexual contact		0.05	[5]
Average number of sexual partners acquired			[24]
Rate of progression from to class		0.52	Assumed
Rate of progression from HIV to AIDS			Assumed
Rate of progression from latent to advanced HCV			Assumed
Natural mortality rate		0.0158	Calculated
Rate of progression from acute to latent HCV		2	[18]
Recruitment rate		602095	Calculated
Amplification factor for individuals in class		1.0001	[15]
Amplification factor for individuals in class		1.001	[5]
Amplification factor for individuals in class		1.0001	[15]
Enhancement factor for increased risk of being infected with HIV by a coinfected individual		1.0002	[5]
Enhancement factor for increased risk of being infected with HCV by a coinfected individual		1.0002	[15]
Rate of spontaneous clearance of acute HCV		0.27	[5]
Reduction factor for risk of acute HCV spontaneous clearance in presence of coinfection		0.25	[5]

Those with have [1, 4], [0.069, 0.1], and [0.095, 0.1].