Identification of the Key Genes Involved in the Effect of Folic Acid on Endothelial Progenitor Cell Transcriptome of Patients with Type 1 Diabetes

Table 1

The top 10 upregulated and downregulated genes after FA treatment.

Gene name	value	Ave nontreatment	Ave treatment	Fc	Regulation
TFRC	0.006293	11.00542	12.23194	2.340016	Upregulated
ZFAND5	0.008766	10.48779	11.68049	2.285802	Upregulated
PPA2	0.008097	10.19328	11.31317	2.173302	Upregulated
LIMS1	0.004958	9.447019	10.47183	2.034697	Upregulated
SPTLC1	0.007231	9.948845	10.89993	1.933331	Upregulated
GPR183	0.008343	10.03497	10.92472	1.852857	Upregulated
STRAP	0.006873	9.901829	10.78517	1.844646	Upregulated
XPO1	0.003324	9.896716	10.76951	1.831212	Upregulated
RAB1A	0.002892	11.08631	11.94823	1.81746	Upregulated
UGP2	0.002848	10.00758	10.86298	1.80927	Upregulated
C19orf24	0.008067	11.64242	11.01402	0.646894	Downregulated
PBX2	0.0019	10.39015	9.723368	0.62991	Downregulated
CCDC106	0.007927	10.40376	9.722742	0.623726	Downregulated
SPATA20	0.00734	10.03424	9.332935	0.615015	Downregulated
PPP6R1	3.43E-05	9.85842	9.156729	0.614851	Downregulated
S100A10	0.007334	11.94692	11.22914	0.608032	Downregulated
PDLIM1	0.006748	9.121195	8.402882	0.607808	Downregulated
HVCN1	0.009486	10.39443	9.670834	0.605587	Downregulated
LHPP	0.000472	9.838647	9.111007	0.603891	Downregulated
LTBP2	0.002257	9.206243	8.462812	0.597317	Downregulated
TMEM156	0.008418	10.49832	9.638557	0.551042	Downregulated