Computational and Mathematical Methods in Medicine / 2020 / Article / Fig 6

Research Article

A Lead Field Two-Domain Model for Longitudinal Neural Tracts—Analytical Framework and Implications for Signal Bandwidth

Figure 6

(a) Axonal potential generated by a single axon of 10 µm diameter at a depth of 50. The conductivity ratio was set to . Isopotential lines are shown in steps of 0.1 nV. Circles indicate the location of the four observation leads which are depicted in (b). (b) The green solid trace depicts the axonal potential at the origin. Shifting the observation lead by 50 mm along the axon (green dashed line) introduced a time shift of 0.83 ms while preserving signal morphology. Lead displacements in a direction perpendicular to the axon are indicated by a magenta trace () and an orange trace (). With increasing distance from the axon amplitude decreased (peak-to-peak amplitude 1.24 nV, 0.89 nV, and 0.44 nV). Furthermore, the shape of the negative peak broadened which was also reflected by a decreasing peak frequency (300 Hz, 265 Hz, and 210 Hz).

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