[Retracted] miR-215 Inhibits Colorectal Cancer Cell Migration and Invasion via Targeting Stearoyl-CoA Desaturase

Figure 2

SCD is a direct target gene of miR-215. (a) The top 20 DEmiRNAs in GSE35834. (b) The Venn diagram of miRNAs that regulate SCD. (c) The targeting sites of miR-215 on SCD 3UTR and the corresponding mutant sequences. (d) qRT-PCR is used to detect the expression of miR-215 in cancer tissue and paracancerous tissue (, ). (e) Relative luciferase activity in HT29 cells after cotransfection with WT or MUT SCD and miR-215 mimic or NC (, , compared to NC). (f) SCD expression on mRNA level in HT29 cells transfected with the miR-215 mimic or NC (, compared to NC). (g) SCD expression on the protein level in HT29 cells transfected with the miR-215 mimic or NC. (h) The correlation between miR-215 and SCD expression in clinical specimens (, compared to NC).

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