Holistic View on Cell Survival and DNA Damage: How Model-Based Data Analysis Supports Exploration of Dynamics in Biological Systems

Figure 3

High-level illustration of the MHR model [27]. The boxes depict the chain structure with the populations ; the arrows denote how cells accumulate hits (to the right), undergo cell death (to the top), or undergo repair (to the left). Below the chain, comet assay pictures conceptually illustrate how comets with increasingly high relative tail intensities are mapped to populations with increasingly high numbers of hits.