Research Article

Holistic View on Cell Survival and DNA Damage: How Model-Based Data Analysis Supports Exploration of Dynamics in Biological Systems

Table 1

Summary of model parameters including their search space. The last column indicates the result of parameter search (see Section 2.6).

ParameterDescriptionSearch space

Radiosensitivity (Gy)
Repair rate constant (h)
Elimination rate constant (h)
TBDE weighting factor (Gy)
TBDE rate constant (h)
Repair protein deactivation rate (h)
Repair protein activation rate (h)
Hyperthermia weighing factor