Application of Optimal Control to Influenza Pneumonia Coinfection with Antiviral Resistance

Table 2

Description and values of the different parameters used.

Parameter	Description	Value	Reference.
π	Recruitment rate	0.0381	Assumed
	Transmission rate of wild-type influenza strain	0.0102 day	Assumed
	Transmission rate of resistant influenza strain	0.00026 day	Assumed
	Transmission rate of pneumonia	0.000162 day	Reference [41]
	Recovery rate of influenza for individuals in class	0.07143 day	Reference [42]
	Recovery rate of influenza for individuals in class	0.0333 day	Assumed
	Recovery rate of influenza for individuals in class	0.04762 day	Reference [43].
	Recovery rate of influenza for individuals in class	0.0222 day	Assumed
	Recovery rate of pneumonia for individuals in class	0.033 day	Reference [41]
	Recovery rate of pneumonia for individuals in class	0.033 day	Reference [41]
	Recovery rate of both influenza and pneumonia for individuals in class	0.0166 day	Assumed
	Recovery rate of both influenza and pneumonia for individuals in class	0.0166 day	Assumed
	Rate of losing immunity for influenza	0.00833 day	Reference [44]
	Rate of losing immunity for pneumonia	0.00833 day	Assumed
	Rate of losing immunity for influenza pneumonia coinfection	0.00833 day	Assumed
b	Rate of developing antiviral resistance	0.0118	Assumed
	Wild-type influenza strain-induced death rate	0.01	Reference [45]
	Resistant influenza strain-induced death rate	0.021	Assumed
	class disease-induced death rate	0.05	Assumed
	class disease-induced death rates	0.05	Assumed
	Average human lifespan	days	Reference [46]