Potential Genes Associated with the Survival of Lung Adenocarcinoma Were Identified by Methylation

Table 4

The most significantly enriched signaling pathways.

Gene	MSigDB collection	Gene set name	NES	val	FDR
NEDD4	c2.cp.kegg.v7.1.symbols.gmt	KEGG_FOCAL_ADHESION	2.666	0.002	0.008
		KEGG_REGULATION_OF_ACTIN_CYTOSKELETON	2.523	0.002	0.008
		KEGG_ECM_RECEPTOR_INTERACTION	2.511	0.002	0.008
	c5.bp.v7.1.symbols.gmt	GO_GRANULOCYTE_MIGRATION	2.562	0.002	0.011
		GO_DEFENSE_RESPONSE_TO_VIRUS	2.511	0.002	0.011
		GO_SUBSTRATE_ADHESION_DEPENDENT_CELL_SPREADING	2.462	0.002	0.011
ASB16	c2.cp.kegg.v7.1.symbols.gmt	KEGG_TASTE_TRANSDUCTION	1.701	0.002	0.088
		KEGG_ABC_TRANSPORTERS	1.605	0.006	0.088
		KEGG_LINOLEIC_ACID_METABOLISM	1.518	0.031	0.139
	c5.bp.v7.1.symbols.gmt	GO_MRNA_SPLICE_SITE_SELECTION	1.935	0.001	0.133
		GO_HISTONE_H3_K27_METHYLATION	1.893	0.001	0.133
		GO_EXTRACELLULAR_TRANSPORT	1.871	0.001	0.133

NES: normalized enrichment score; FDR: false discovery rate.