|
Parameter (unit) | Description and sources | First patient | Second patient |
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| Tumor growth rate [40, 42]. | | |
| Half saturation constant of the tumor killing rate [46]. | | |
| 1/b is the tumor carrying capacity [40, 42]. | | |
| Fractional no ligand-transduced tumor cell kill by natural killer cells [40, 42, 52]. | | |
| Maximum tumor killing rate by cytokine [44, 46]. | | |
| Saturation level of fractional tumor cell kill by CD8+T cells. Primed with ligand transduced cells, challenged with ligand transduced [40, 42, 52]. | | |
| Fraction of circulating lymphocytes that become natural killer cells [40, 42]. | | |
| Death rate of natural killer cells [40, 42]. | | |
| Maximum natural killer cells recruitment by ligand transduced tumor cells [40, 42, 52]. | | |
| Steepness of CD8+T cell recruitment curve by cytokine [40, 42]. | | |
| Steepness coefficient of the natural killer cell recruitment curve [40, 42]. | | |
| Maximum CD8+T cell recruitment rate. Primed with ligand transduced cells, challenged with ligand transduced cells [40, 42, 52]. | | |
| Steepness coefficient of the CD8+T cell recruitment curve [40, 42, 52]. | | |
| Fractional tumor cells kill by chemotherapy [40, 42]. | | |
| Fractional natural killer cells kill by chemotherapy [40, 42]. | | |
| Fractional CD8+T cells kill by chemotherapy [40, 42]. | | |
| Fractional circulating lymphocytes cells kill by chemotherapy [40, 42]. | | |
| Exponent of fractional tumor cell kill by CD8+T cells. Primed with ligand transduced cells, challenged with ligand transduced cells [40, 42]. | | |
| Death rate of CD8+T cells [40, 42]. | | |
| Natural killer cell inactivation rate by tumor cells [40, 42]. | | |
| Maximum CD8+T cell recruitment rate by cytokine [40, 42]. | | |
| CD8+T cell inactivation rate by tumor cells [40, 42]. | | |
| Rate of which CD8+T cells are stimulated to be produced; as a result, tumor cells killed by natural killer cells [40, 42]. | | |
| Rate of which CD8+T cells are stimulated to be produced; as a result, tumor cells interaction with circulating lymphocytes [40, 42]. | | |
| Steepness coefficient of tumor-CD8+T cell lysis term D. Primed with ligand transduced cells, challenged with ligand transduced [40, 42]. | | |
| Regulatory function by natural killer cells of CD8+T cells [40, 42]. | | |
| Constant source of circulating lymphocytes [40, 42]. | | |
| Half saturation constant of the CD4+T cells production rate [46, 53]. | | |
| Half saturation constant of cytokine production rate [44, 46]. | | |
| Natural death and differentiation of circulating lymphocytes [40, 42]. | | |
| Maximum CD4+T cells production rate [44, 46]. | | |
| Maximum production rate of cytokine [44, 46]. | | |
| Rate of chemotherapy drug decay [40, 42]. | | |
| Natural death rate of CD4+T cells [45, 46]. | | |
| Rate of cytokine decay [40, 42]. | | |
| Loss rate of CD4+T cells due to interaction with tumor cells [44, 46]. | | |
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