Computational and Mathematical Methods in Medicine

Research Article

Effects of Single-Nucleotide Polymorphisms in Calmodulin-Dependent Protein Kinase Kinase 2 (CAMKK2): A Comprehensive Study

Table 1

Deleterious SNPs predicted from homology-based tools, consensus-based tools, and MutPred.
Homology-based toolsConsensus-based methodsMutPred
MutationSNPNexusPROVEANMutation AccessorPredictionMeta-SNPPredictSNPSNPs&GOPredictionMutPred
E465HDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousNeutral
R508CDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousNeutral
R504WDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousNeutral
C461SDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousNeutral
D458HDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousNeutralNeutralDeleteriousNeutral
D458LDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousNeutral
P453QDeleteriousDeleteriousNeutralDeleteriousDeleteriousNeutralDeleteriousDeleteriousNeutral
P453CDeleteriousDeleteriousNeutralDeleteriousDeleteriousNeutralDeleteriousDeleteriousNeutral
W445CDeleteriousDeleteriousNeutralDeleteriousDeleteriousDeleteriousNeutralDeleteriousNeutral
H443YDeleteriousDeleteriousNeutralDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousNeutral
A182IDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousNeutral
P438RDeleteriousDeleteriousNeutralDeleteriousNeutralNeutralNeutralNeutralNeutral
M193TDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousNeutral
I435ADeleteriousDeleteriousNeutralDeleteriousDeleteriousNeutralDeleteriousDeleteriousDiseased
V195ADeleteriousDeleteriousDeleteriousDeleteriousDeleteriousNeutralDeleteriousDeleteriousDiseased
R217WDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousNeutralDeleteriousNeutral
P389TDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousDiseased
F366YDeleteriousDeleteriousNeutralDeleteriousNeutralNeutralNeutralNeutralDiseased
L419HDeleteriousDeleteriousNeutralDeleteriousNeutralDeleteriousDeleteriousDeleteriousDiseases
R492CDeleteriousDeleteriousNeutralDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousNeutral
V249MDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousDiseased
V487MDeleteriousDeleteriousNeutralDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousNeutral
Y183CDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousNeutralNeutralNeutralDiseased
N460KDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousNeutral
L318ADeleteriousDeleteriousNeutralDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousDiseased
M265TDeleteriousDeleteriousNeutralDeleteriousNeutralNeutralNeutralNeutralDiseased
M265DDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousDiseased
R311CDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousDiseased
V233LDeleteriousDeleteriousNeutralDeleteriousNeutralNeutralNeutralNeutralNeutral
P444LDeleteriousDeleteriousNeutralDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousNeutral
E432ADeleteriousDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousDeleteriousNeutral
V275TDeleteriousDeleteriousDeleteriousDeleteriousNeutralNeutralNeutralNeutralDiseased
P389TDeleteriousDeleteriousDeleteriousDeleteriousNeutralDeleteriousDeleteriousDeleteriousDiseased