Mathematical Prostate Cancer Evolution: Effect of Immunotherapy Based on Controlled Vaccination Strategy

<div>The possible scenarios of PC evolution for different tumour growth rate <i>r</i>. Each line represents virtual patient labelled by <i>r</i> parameter. Quasi-vertical lines show the moments of vaccinations, while their heights correspond to the population of vaccinations cells rescaled by <span class="nowrap"><svg height="11.7978pt" id="M85" style="vertical-align:-0.2063999pt" version="1.1" viewbox="-0.0498162 -11.5914 17.5728 11.7978" width="17.5728pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M384 0V27C293 34 287 42 287 114V635C232 613 172 594 109 583V559L157 557C201 555 205 550 205 499V114C205 42 199 34 109 27V0H384Z"></path></g><g transform="matrix(.013,0,0,-0.013,6.24,0)"><path d="M241 635C89 635 35 457 35 312C35 153 89 -12 240 -12C390 -12 443 166 443 312C443 466 390 635 241 635ZM238 602C329 602 354 454 354 312C354 172 330 22 240 22C152 22 124 173 124 313S148 602 238 602Z"></path></g><g transform="matrix(.0091,0,0,-0.0091,12.527,-5.741)"><path d="M462 177V227H365V632H320C217 496 116 350 21 208V177H284V109C284 43 280 38 190 31V0H451V31C369 38 365 43 365 108V177H462ZM284 227H88C155 336 218 430 282 519H284V227Z"></path></g></svg>.</span></div>

Computational and Mathematical Methods in Medicine

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Figure 4

Figure 4: Mathematical Prostate Cancer Evolution: Effect of Immunotherapy Based on Controlled Vaccination Strategy 